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Rare neurodegenerative diseases are characterized by high heterogeneity and high clinical complexity, as well as low incidence and prevalence, thus making tracking small numbers of incident cases in the general population very challenging. Since it is not possible to use classical cohort studies to estimate the incidence of these rare diseases, we can “reconstruct” a theoretical cohort using case

https://www.lupop.lu.se/article/reconstructed-cohort-design-method-study-rare-neurodegenerative-diseases-population-based-settings - 2026-01-07

The share of contact allergy to MCI/MI 0.215% aq., MCI/MI 0.02% aq., and MI 0.2% aq. varied in the test centers between 7.9% and 25.9%, 3.2% and 10.3%, and 5.8% and 12.3%, respectively. MCI/MI 0.215% aq. detected significantly more patch‐test positive individuals than both MCI/MI 0.02% aq. (P < .001) and MI 0.2% aq. (P < .001), as well as either one of MCI/MI and MI (P < .001). In the patients onl

https://www.lupop.lu.se/article/can-patch-testing-methylchloroisothiazolinonemethylisothiazolinone-be-optimized-using-new-diagnostic - 2026-01-07

We aimed to assess the patient experience of informed consent (IC) during acute myocardial infarction (AMI) in a sub-study of the VALIDATE-SWEDEHEART trial. The original trial compared two anticoagulant agents in patients undergoing coronary intervention. A witnessed oral IC was required prior to randomization in patients with ST-segment elevation myocardial infarction, which was subsequently comp

https://www.lupop.lu.se/article/patient-experience-informed-consent-process-during-acute-myocardial-infarction - 2026-01-07

Left atrial appendage occlusion (LAAO) to prevent stroke in patients with atrial fibrillation has been evaluated in 2 randomized trials; post-approval clinical data are limited. New publication in J Am Coll Cardiol

https://www.lupop.lu.se/article/ncdr-left-atrial-appendage-occlusion-registry - 2026-01-07

For STEMI patients admitted for primary percutaneous coronary intervention from 2007-2010, the latest ECGs recorded before STEMI were exported in digital format. After excluding ECGs with paced rhythm and QRS duration ≥120 ms, the remaining ECGs were processed using the Glasgow algorithm allowing automatic ER detection. The association between ER pattern and VT/VF during the first 48 hours of STEM

https://www.lupop.lu.se/article/early-repolarization-pattern-ecg-recorded-acute-coronary-event-does-not-predict-ventricular - 2026-01-07

Heart failure (HF) has emerged as a global public health problem that affects both low and high-income countries. The high HF burden and the need for resource-intensive treatments often lead to health system crisis in resource-poor settings. Data on prevailing practice patterns and long-term clinical outcomes of HF are scarce from the low and middle-income countries. Nationally representative HF d

https://www.lupop.lu.se/article/national-heart-failure-registry-india-design-and-methods - 2026-01-07

There were no significant differences in 25(OH)D levels between MDD and controls (p = 0.24) or between MDD with and without SI (p = 0.61). However, 25(OH)D was negatively correlated with all measured inflammatory markers; these correlations were stronger in MDD subjects, and particularly in those with SI. MDD status significantly moderated the relationships between 25(OH)D and NLR (p = 0.03), and

https://www.lupop.lu.se/article/vitamin-d-and-inflammation-major-depressive-disorder - 2026-01-07

Globally, an estimated 350 million people are affected by a rare disease diagnosis. Knowledge limitations persist for the majority of rare conditions due to systemic and structural challenges in healthcare and research. Disease-specific patient populations are often small and geographically dispersed; funding support for research is restricted; and diagnostic delays are common due to disease compl

https://www.lupop.lu.se/article/establishing-patient-registries-rare-diseases-rationale-and-challenges - 2026-01-07

DORIS är ett verktyg som ska gå att använda genom hela processen för att göra forskningsdata tillgängliga: från beskrivning av forskningsdata till beställning av data för återanvändning eller granskning. Utvecklingen av systemet är uppdelat i flera olika faser. Läs mer på https://snd.gu.se/sv/nyheter/doris-gor-det-enklare-att-dela-data-snd.

https://www.lupop.lu.se/article/doris-gor-det-enklare-att-dela-data-snd - 2026-01-07

A call for proposals for funding of Nordic and Nordic-Estonian/Latvian collaboration projects on health data research on COVID-19 is now announced. The application deadline is 16 June 2020 13 CEST. Read more at https://www.nordforsk.org/calls/nordic-health-data-research-projects-co….

https://www.lupop.lu.se/article/nordic-health-data-research-projects-covid-19 - 2026-01-07

Ett särskilt aktuellt register dessa dagar är Svenska Intensivvårdsregistret, SIR, som dagligen rapporterar om antalet inlagda patienter med covid-19 på svenska intensivvårdsavdelningar. Representanter från SIR har arbetat intensivt tillsammans med Vetenskapsrådet för att dokumentera registrets innehåll i RUT och på så sätt göra det mer tillgängligt för forskning. Läs mer här.

https://www.lupop.lu.se/article/svenska-intensivvardsregistret-sir-har-anslutits-till-metadataverktyget-rut - 2026-01-07

Nu finns möjlighet att lyssna på en initierad podd i två delar där forskare samtalar om virusets spridning, lärdomar från spanska sjukan samt ekonomiska konsekvenser av den nedstängning av världen som vi nu upplever. Poddcasten är framtagen som samarbete mellan Centrum för ekonomisk demografi (CED) vid Ekonomihögskolan i Lund och LU Futura - Lunds universitets tankesmedja för framtidsfrågor. Läs m

https://www.lupop.lu.se/article/poddcast-att-forsta-corona-och-dess-konsekvenser - 2026-01-07

Job opening at Galapagos, a Biotech company with offices in Europe in Belgium (Mechelen), France (Romainville), the Netherlands (Leiden), Basel (Switzerland) and in Boston (US). Read more at https://careers.glpg.com/o/principal-biostatistician-belgium-the-nether….

https://www.lupop.lu.se/article/principal-biostatistician-belgium-netherlands-or-switzerland - 2026-01-07

Diabetes registries can be used to monitor the prevalence and incidence of diabetes. Diabetes registries are used in many countries for population management of diabetes, outcomes management, and development of Clinician finding Support Structure, for example, National Diabetes Registry (NDR) in Sweden and Singapore diabetes registry. New publication in Pakistan Journal of Medical Sciences

https://www.lupop.lu.se/article/diabetes-registry-pakistan - 2026-01-07

Temporally and spatially highly resolved information on population characteristics, including demographic profile (e.g. age and sex), ethnicity and socio-economic status (e.g. income, occupation, education), are essential for observational health studies at the small-area level. Time-relevant population data are critical as denominators for health statistics, analytics and epidemiology, to calcula

https://www.lupop.lu.se/article/advances-mapping-population-and-demographic-characteristics-small-area-levels - 2026-01-07

This paper studies the effects of improvements in infant health produced by the introduction of sulphapyridine in the late-1930s as treatment against pneumonia on outcomes in adulthood. Based on longitudinal individual data for the whole population of Sweden 1968–2012 and archival data on the availability of sulphapyridine and applying a difference-in-differences approach, it finds that mitigation

https://www.lupop.lu.se/article/infant-health-and-later-life-labor-market-outcomes-evidence-introduction-sulpha-antibiotics-sweden - 2026-01-07

Effective stewardship of data is a critical precursor to making data FAIR. The goal of this paper is to bring an overview of current state of the art of data management and data stewardship planning solutions (DMP). We begin by arguing why data management is an important vehicle supporting adoption and implementation of the FAIR principles, we describe the background, context and historical develo

https://www.lupop.lu.se/article/data-management-planning-how-requirements-and-solutions-are-beginning-converge-show-all-authors - 2026-01-07

To investigate the risk of cancer in patients with biopsy-proven giant cell arteritis (GCA) from a defined population in southern Sweden. New publication in The Journal of Rheumatology

https://www.lupop.lu.se/article/malignancies-giant-cell-arteritis-population-based-cohort-study - 2026-01-07

PhD-courses of relevance for population research The strategic research area EpiHealth - Epidemiology for Health - together with LUPOP - Lund University Population Research Platform - now opens a call for proposals for new PhD - courses of relevance for population research. We will fund 3 - 5 courses during 2018 related to e.g. epidemiological data analysis, medical statistics, biobank studies, bi

https://www.lupop.lu.se/article/call-proposals - 2026-01-07

Food patterns were extracted using principal component analysis in 1726 individuals (aged 18–71 y, 55% women, mean BMI = 25.5 kg/m2) without diabetes from the population-based Malmö Offspring Study. The gut (fecal) microbiota was analyzed by sequencing the 16S ribosomal RNA gene (V1–V3 region). Prediabetes classification was based on fasting glucose ≥6.0 mmol/L and/or glycated hemoglobin ≥42 mmol/

https://www.lupop.lu.se/article/health-conscious-food-pattern-associated-prediabetes-and-gut-microbiota-malmo-offspring-study - 2026-01-07